Polymyositis complicating D-penicillamine treatment.
نویسندگان
چکیده
منابع مشابه
Polymyositis complicating D-penicillamine treatment.
Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whether D-penicillamine treatment was the sole cause of polymyositis or acted as a...
متن کاملDermatomyositis complicating penicillamine treatment.
A case of dermatomyositis developing during the course of treatment with D-penicillamine in a patient with rheumatoid arthritis is described. Complete remission occurred on withdrawal of the drug. Possible alternative diagnoses are discussed.
متن کاملWilson's disease: assessment of D-penicillamine treatment.
Serum copper and zinc concentrations and 24 hour urinary copper and zinc excretion were determined serially from the beginning of treatment with D-penicillamine in four children with Wilson's disease. The data show a progressive decrease in both serum copper and zinc concentrations in all. Urinary copper excretion gradually levelled off to approximately 50% of initial values, but zinc excretion...
متن کاملTreatment of scleroderma heart by D-penicillamine.
A case of severe diffuse systemic sclerosis with cardiomegaly and cardiac failure is described. Treatment with D-penicillamine caused a pronounced decrease in heart size, together with clinical improvement. The use of penicillamine in scleroderma heart has not previously been reported.
متن کاملA Case of Polymyositis in a Patient with Primary Biliary Cirrhosis Treated with D-Penicillamine
Although D-penicillamine has been used for many rheumatologic diseases, toxicity limits its usefulness in many patients. Polymyositis/dermatomyositis can develop as one of the autoimmune complications of D-penicillamine treatment, but its exact pathogenesis remains unclear. We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy. We...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1991
ISSN: 0032-5473
DOI: 10.1136/pgmj.67.793.1018